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The anus is where stool leaves your body when you go to the bathroom. It is made up of your outer layers of skin and the end of your large intestine. Anal cancer is a disease in which cancer cells form in the tissues of the anus.

Anal cancer is rare. It is more common in smokers and people over 50. You are also at higher risk if you have HPV, have anal sex, or have many sexual partners.

Symptoms include bleeding, pain, or lumps in the anal area. Anal itching and discharge can also be signs of anal cancer.

Doctors use tests that examine the anus to diagnose anal cancer. They include a physical exam, endoscopy, ultrasound, and biopsy.

Treatments include radiation therapy, chemotherapy, and surgery.

NIH: National Cancer Institute

Also called: Colon cancer, Rectal cancer

The colon and rectum are part of the large intestine. Colorectal cancer occurs when tumors form in the lining of the large intestine. It is common in both men and women. The risk of developing colorectal cancer rises after age 50. You’re also more likely to get it if you have colorectal polyps, a family history of colorectal cancer, ulcerative colitis or Crohn’s disease, eat a diet high in fat, or smoke.

Symptoms of colorectal cancer include

  • Diarrhea or constipation
  • A feeling that your bowel does not empty completely
  • Blood (either bright red or very dark) in your stool
  • Stools that are narrower than usual
  • Frequent gas pains or cramps, or feeling full or bloated
  • Weight loss with no known reason
  • Fatigue
  • Nausea or vomiting

Because you may not have symptoms at first, it’s important to have screening tests. Everyone over 50 should get screened. Tests include colonoscopy and tests for blood in the stool. Treatments for colorectal cancer include surgery, chemotherapy, radiation, or a combination. Surgery can usually cure it when it is found early.

NIH: National Cancer Institute

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