Incontinentia Pigmenti—Skin Conditions

Also called: Cutaneous disorders, Dermatologic disorders

Your skin is your body’s largest organ. It covers and protects your body. Your skin

• Holds body fluids in, preventing dehydration
• Keeps harmful microbes out, preventing infections
• Helps you feel things like heat, cold, and pain
• Keeps your body temperature even
• Makes vitamin D when the sun shines on it

Anything that irritates, clogs, or inflames your skin can cause symptoms such as redness, swelling, burning, and itching. Allergies, irritants, your genetic makeup, and certain diseases and immune system problems can cause rashes, hives, and other skin conditions. Many skin problems, such as acne, also affect your appearance.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

• Acrodermatitis (Medical Encyclopedia)
• Cryotherapy (Medical Encyclopedia)
• Cutaneous skin tags (Medical Encyclopedia)
• Dry skin — self-care (Medical Encyclopedia)
• Erythema multiforme (Medical Encyclopedia)
• Granuloma annulare (Medical Encyclopedia)
• Keratosis pilaris (Medical Encyclopedia)
• Lichen planus (Medical Encyclopedia)
• Milia (Medical Encyclopedia)
• Sebaceous cyst (Medical Encyclopedia)
• Seborrheic keratosis (Medical Encyclopedia)
• Skin lesion removal (Medical Encyclopedia)
• Skin lesion removal-aftercare (Medical Encyclopedia)
• Stasis dermatitis and ulcers (Medical Encyclopedia)

Incontinentia pigmenti is a condition that can affect many body systems, particularly the skin. This condition occurs much more often in females than in males.Incontinentia pigmenti is characterized by skin abnormalities that evolve throughout childhood and young adulthood. Many affected infants have a blistering rash at birth and in early infancy, which heals and is followed by the development of wart-like skin growths. In early childhood, the skin develops grey or brown patches (hyperpigmentation) that occur in a swirled pattern. These patches fade with time, and adults with incontinentia pigmenti usually have lines of unusually light-colored skin (hypopigmentation) on their arms and legs.Other signs and symptoms of incontinentia pigmenti can include hair loss (alopecia) affecting the scalp and other parts of the body, dental abnormalities (such as small teeth or few teeth), eye abnormalities that can lead to vision loss, and lined or pitted fingernails and toenails. Most people with incontinentia pigmenti have normal intelligence; however, this condition may affect the brain. Associated problems can include delayed development or intellectual disability, seizures, and other neurological problems.