Meningococcal Infections—Endocarditis

Endocarditis, also called infective endocarditis (IE), is an inflammation of the inner lining of the heart. The most common type, bacterial endocarditis, occurs when germs enter your heart. These germs come through your bloodstream from another part of your body, often your mouth. Bacterial endocarditis can damage your heart valves. If untreated, it can be life-threatening. It is rare in healthy hearts.

Risk factors include having

• An abnormal or damaged heart valve
• An artificial heart valve
• Congenital heart defects

The signs and symptoms of IE can vary from person to person. They also can vary over time in the same person. Symptoms you might notice include fever, shortness of breath, fluid buildup in your arms or legs, tiny red spots on your skin, and weight loss. Your doctor will diagnose IE based on your risk factors, medical history, signs and symptoms, and lab and heart tests.

Early treatment can help you avoid complications. Treatment usually involves high-dose antibiotics. If your heart valve is damaged, you may need surgery.

If you’re at risk for IE, brush and floss your teeth regularly, and have regular dental checkups. Germs from a gum infection can enter your bloodstream. If you are at high risk, your doctor might prescribe antibiotics before dental work and certain types of surgery.

NIH: National Heart, Lung, and Blood Institute

• Culture-negative endocarditis (Medical Encyclopedia)
• Endocarditis (Medical Encyclopedia)
• Endocarditis – children (Medical Encyclopedia)

Meningococci are a type of bacteria that cause serious infections. The most common infection is meningitis, which is an inflammation of the thin tissue that surrounds the brain and spinal cord. Meningococci can also cause other problems, including a serious bloodstream infection called sepsis.

Meningococcal infections can spread from person to person. Risk factors include

• Age – it is more common in infants, teens, and young adults
• Living in close quarters, such as in college dorms or military settings
• Certain medical conditions, such as not having a spleen
• Travel to areas where meningococcal disease is common

In its early stages, you may have flu-like symptoms and a stiff neck. But the disease can progress quickly and can be fatal. Early diagnosis and treatment are extremely important. Lab tests on your blood and cerebrospinal fluid can tell if you have it. Treatment is with antibiotics. Since the infection spreads from person to person, family members may also need to be treated.

A vaccine can prevent meningococcal infections.

• Meningococcemia (Medical Encyclopedia)
• Waterhouse-Friderichsen syndrome (Medical Encyclopedia)