Metabolic Disorders—Lymphoma

Also called: Non-Hodgkin lymphoma

Lymphoma is a cancer of a part of the immune system called the lymph system. There are many types of lymphoma. One type is Hodgkin disease. The rest are called non-Hodgkin lymphomas.

Non-Hodgkin lymphomas begin when a type of white blood cell, called a T cell or B cell, becomes abnormal. The cell divides again and again, making more and more abnormal cells. These abnormal cells can spread to almost any other part of the body. Most of the time, doctors don’t know why a person gets non-Hodgkin lymphoma. You are at increased risk if you have a weakened immune system or have certain types of infections.

Non-Hodgkin lymphoma can cause many symptoms, such as

• Swollen, painless lymph nodes in the neck, armpits or groin
• Unexplained weight loss
• Fever
• Soaking night sweats
• Coughing, trouble breathing or chest pain
• Weakness and tiredness that don’t go away
• Pain, swelling or a feeling of fullness in the abdomen

Your doctor will diagnose lymphoma with a physical exam, blood tests, a chest x-ray, and a biopsy. Treatments include chemotherapy, radiation therapy, targeted therapy, biological therapy, or therapy to remove proteins from the blood. Targeted therapy uses substances that attack cancer cells without harming normal cells. Biologic therapy boosts your body’s own ability to fight cancer. If you don’t have symptoms, you may not need treatment right away. This is called watchful waiting.

NIH: National Cancer Institute

• After chemotherapy – discharge (Medical Encyclopedia)
• B-cell leukemia/lymphoma panel (Medical Encyclopedia)
• Bone marrow transplant (Medical Encyclopedia)
• Burkitt lymphoma (Medical Encyclopedia)
• Lymph node biopsy (Medical Encyclopedia)
• Non-Hodgkin lymphoma (Medical Encyclopedia)
• Non-Hodgkin lymphoma – children (Medical Encyclopedia)
• Understanding Chemotherapy – NIH – Easy-to-Read (National Cancer Institute) – PDF
• What to Know about Brachytherapy (A Type of Internal Radiation Therapy) – NIH – Easy-to-Read (National Cancer Institute) – PDF
• What to Know about External Beam Radiation Therapy – NIH – Easy-to-Read (National Cancer Institute) – PDF

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body’s fuel. Your body can use this fuel right away, or it can store the energy in your body tissues, such as your liver, muscles, and body fat.

A metabolic disorder occurs when abnormal chemical reactions in your body disrupt this process. When this happens, you might have too much of some substances or too little of other ones that you need to stay healthy. There are different groups of disorders. Some affect the breakdown of amino acids, carbohydrates, or lipids. Another group, mitochondrial diseases, affects the parts of the cells that produce the energy.

You can develop a metabolic disorder when some organs, such as your liver or pancreas, become diseased or do not function normally. Diabetes is an example.

• Acidosis (Medical Encyclopedia)
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