Lead Poisoning—Gout

Also called: Gouty arthritis

Gout is a common, painful form of arthritis. It causes swollen, red, hot and stiff joints.

Gout happens when uric acid builds up in your body. Uric acid comes from the breakdown of substances called purines. Purines are in your body’s tissues and in foods, such as liver, dried beans and peas, and anchovies. Normally, uric acid dissolves in the blood. It passes through the kidneys and out of the body in urine. But sometimes uric acid can build up and form needle-like crystals. When they form in your joints, it is very painful. The crystals can also cause kidney stones.

Often, gout first attacks your big toe. It can also attack ankles, heels, knees, wrists, fingers, and elbows. At first, gout attacks usually get better in days. Eventually, attacks last longer and happen more often.

You are more likely to get gout if you

• Are a man
• Have family member with gout
• Are overweight
• Drink alcohol
• Eat too many foods rich in purines

Gout can be hard to diagnose. Your doctor may take a sample of fluid from an inflamed joint to look for crystals. You can treat gout with medicines.

Pseudogout has similar symptoms and is sometimes confused with gout. However, it is caused by calcium phosphate, not uric acid.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

• Calcium pyrophosphate arthritis (Medical Encyclopedia)
• Gout (Medical Encyclopedia)
• Uric acid – blood (Medical Encyclopedia)
• Uric acid – urine (Medical Encyclopedia)

Also called: Plumbism

Lead is a metal that occurs naturally in the earth’s crust. Lead can be found in all parts of our environment. Much of it comes from human activities such as mining and manufacturing. Lead used to be in paint; older houses may still have lead paint. You could be exposed to lead by

• Eating food or drinking water that contains lead. Water pipes in older homes may contain lead.
• Working in a job where lead is used
• Using lead in a hobby, such as making stained glass or lead-glazed pottery
• Using folk remedies such as herbs or foods that contain lead

Breathing air, drinking water, eating food, or swallowing or touching dirt that contains lead can cause many health problems. Lead can affect almost every organ and system in your body. In adults, lead can increase blood pressure and cause infertility, nerve disorders, and muscle and joint pain. It can also make you irritable and affect your ability to concentrate and remember.

Lead is especially dangerous for children. A child who swallows large amounts of lead may develop anemia, severe stomachache, muscle weakness, and brain damage. Even at low levels, lead can affect a child’s mental and physical growth.

Agency for Toxic Substances Disease Registry

• Lead – nutritional considerations (Medical Encyclopedia)
• Lead levels – blood (Medical Encyclopedia)
• Lead poisoning (Medical Encyclopedia)
• Lead Toxicity (Agency for Toxic Substances and Disease Registry) – PDF