Lymphoma—Lymphatic Diseases

The lymphatic system is a network of tissues and organs. It is made up of

• Lymph – a fluid that contains white blood cells that defend against germs
• Lymph vessels – vessels that carry lymph throughout your body. They are different from blood vessels.
• Lymph nodes – glands found throughout the lymph vessels. Along with your spleen, these nodes are where white blood cells fight infection.

Your bone marrow and thymus produce the cells in lymph. They are part of the system, too.

The lymphatic system clears away infection and keeps your body fluids in balance. If it’s not working properly, fluid builds in your tissues and causes swelling, called lymphedema. Other lymphatic system problems can include infections, blockage, and cancer.

• Cancer and lymph nodes (Medical Encyclopedia)
• Cystic hygroma (Medical Encyclopedia)
• Groin lump (Medical Encyclopedia)
• Lymph node biopsy (Medical Encyclopedia)
• Lymph system (Medical Encyclopedia)
• Lymphadenitis (Medical Encyclopedia)
• Lymphangitis (Medical Encyclopedia)
• Lymphofollicular hyperplasia (Medical Encyclopedia)
• Neck lump (Medical Encyclopedia)
• Swollen lymph nodes (Medical Encyclopedia)

Also called: Non-Hodgkin lymphoma

Lymphoma is a cancer of a part of the immune system called the lymph system. There are many types of lymphoma. One type is Hodgkin disease. The rest are called non-Hodgkin lymphomas.

Non-Hodgkin lymphomas begin when a type of white blood cell, called a T cell or B cell, becomes abnormal. The cell divides again and again, making more and more abnormal cells. These abnormal cells can spread to almost any other part of the body. Most of the time, doctors don’t know why a person gets non-Hodgkin lymphoma. You are at increased risk if you have a weakened immune system or have certain types of infections.

Non-Hodgkin lymphoma can cause many symptoms, such as

• Swollen, painless lymph nodes in the neck, armpits or groin
• Unexplained weight loss
• Fever
• Soaking night sweats
• Coughing, trouble breathing or chest pain
• Weakness and tiredness that don’t go away
• Pain, swelling or a feeling of fullness in the abdomen

Your doctor will diagnose lymphoma with a physical exam, blood tests, a chest x-ray, and a biopsy. Treatments include chemotherapy, radiation therapy, targeted therapy, biological therapy, or therapy to remove proteins from the blood. Targeted therapy uses substances that attack cancer cells without harming normal cells. Biologic therapy boosts your body’s own ability to fight cancer. If you don’t have symptoms, you may not need treatment right away. This is called watchful waiting.

NIH: National Cancer Institute

• After chemotherapy – discharge (Medical Encyclopedia)
• B-cell leukemia/lymphoma panel (Medical Encyclopedia)
• Bone marrow transplant (Medical Encyclopedia)
• Burkitt lymphoma (Medical Encyclopedia)
• Lymph node biopsy (Medical Encyclopedia)
• Non-Hodgkin lymphoma (Medical Encyclopedia)
• Non-Hodgkin lymphoma – children (Medical Encyclopedia)
• Understanding Chemotherapy – NIH – Easy-to-Read (National Cancer Institute) – PDF
• What to Know about Brachytherapy (A Type of Internal Radiation Therapy) – NIH – Easy-to-Read (National Cancer Institute) – PDF
• What to Know about External Beam Radiation Therapy – NIH – Easy-to-Read (National Cancer Institute) – PDF