Your liver makes a digestive juice called bile. Your gallbladder stores it between meals. When you eat, your gallbladder pushes the bile into tubes called bile ducts. They carry the bile to your small intestine. The bile helps break down fat. It also helps the liver get rid of toxins and wastes.
Different diseases can block the bile ducts and cause a problem with the flow of bile:
- Gallstones, which can increase pressure in the gallbladder and cause a gallbladder attack. The pain usually lasts from one to several hours.
- Cancer
- Infections
- Birth defects, such as biliary atresia. It is the most common reason for liver transplants in children in the United States.
- Inflammation, which can cause scarring. Over time, this can lead to liver failure.
NIH: National Institute of Diabetes and Digestive and Kidney Diseases
The pancreas is a gland behind your stomach and in front of your spine. It produces juices that help break down food and hormones that help control blood sugar levels. Problems with the pancreas can lead to many health problems. These include
- Pancreatitis, or inflammation of the pancreas: This happens when digestive enzymes start digesting the pancreas itself
- Pancreatic cancer
- Cystic fibrosis, a genetic disorder in which thick, sticky mucus can also block tubes in your pancreas
The pancreas also plays a role in diabetes. In type 1 diabetes, the beta cells of the pancreas no longer make insulin because the body’s immune system has attacked them. In type 2 diabetes, the pancreas loses the ability to secrete enough insulin in response to meals.