Plague—Meningitis

Also called: Spinal meningitis

Meningitis is inflammation of the thin tissue that surrounds the brain and spinal cord, called the meninges. There are several types of meningitis. The most common is viral meningitis. You get it when a virus enters the body through the nose or mouth and travels to the brain. Bacterial meningitis is rare, but can be deadly. It usually starts with bacteria that cause a cold-like infection. It can cause stroke, hearing loss, and brain damage. It can also harm other organs. Pneumococcal infections and meningococcal infections are the most common causes of bacterial meningitis.

Anyone can get meningitis, but it is more common in people with weak immune systems. Meningitis can get serious very quickly. You should get medical care right away if you have

• A sudden high fever
• A severe headache
• A stiff neck
• Nausea or vomiting

Early treatment can help prevent serious problems, including death. Tests to diagnose meningitis include blood tests, imaging tests, and a spinal tap to test cerebrospinal fluid. Antibiotics can treat bacterial meningitis. Antiviral medicines may help some types of viral meningitis. Other medicines can help treat symptoms.

There are vaccines to prevent some of the bacterial infections that cause meningitis.

NIH: National Institute of Neurological Disorders and Stroke

• Cerebral spinal fluid (CSF) collection (Medical Encyclopedia)
• Cerebrospinal fluid culture (Medical Encyclopedia)
• Meningitis (Medical Encyclopedia)
• Meningitis – cryptococcal (Medical Encyclopedia)
• Meningitis – gram-negative (Medical Encyclopedia)
• Meningitis – H. influenzae (Medical Encyclopedia)
• Meningococcal ACWY Vaccines – MenACWY and MPSV4: What You Need to Know (Centers for Disease Control and Prevention) – PDF
• Pneumococcal Conjugate Vaccine (PCV13): What You Need to Know (Centers for Disease Control and Prevention) – PDF
• Pneumococcal Polysaccharide Vaccine: What You Need to Know (Immunization Action Coalition) – PDF
• Pneumococcal Polysaccharide Vaccine: What You Need to Know (Centers for Disease Control and Prevention) – PDF

Also called: Bubonic plague, Pneumonic plague

Plague is an infection caused by the bacterium Yersinia pestis. The bacteria are found mainly in rats and in the fleas that feed on them. People and other animals can get plague from rat or flea bites. In the past, plague destroyed entire civilizations. Today plague is uncommon, due to better living conditions and antibiotics.

There are three forms of plague:

• Bubonic plague causes the tonsils, adenoids, spleen, and thymus to become inflamed. Symptoms include fever, aches, chills, and tender lymph glands.
• In septicemic plague, bacteria multiply in the blood. It causes fever, chills, shock, and bleeding under the skin or other organs.
• Pneumonic plague is the most serious form. Bacteria enter the lungs and cause pneumonia. People with the infection can spread this form to others. This type could be a bioterror agent.

Lab tests can diagnose plague. Treatment is a strong antibiotic. There is no vaccine.

NIH: National Institute of Allergy and Infectious Diseases

• Plague (Medical Encyclopedia)