Gangrene is the death of tissues in your body. It happens when a part of your body loses its blood supply. Gangrene can happen on the surface of the body, such as on the skin, or inside the body, in muscles or organs. Causes include

Skin symptoms may include a blue or black color, pain, numbness, and sores that produce a foul-smelling discharge. If the gangrene is internal, you may run a fever and feel unwell, and the area may be swollen and painful.

Gangrene is a serious condition. It needs immediate attention. Treatment includes surgery, antibiotics, and oxygen therapy. In severe cases an amputation may be necessary.

Also called: Raynaud’s phenomenon

Raynaud’s disease is a rare disorder of the blood vessels, usually in the fingers and toes. It causes the blood vessels to narrow when you are cold or feeling stressed. When this happens, blood can’t get to the surface of the skin and the affected areas turn white and blue. When the blood flow returns, the skin turns red and throbs or tingles. In severe cases, loss of blood flow can cause sores or tissue death.

Primary Raynaud’s happens on its own. The cause is not known. There is also secondary Raynaud’s, which is caused by injuries, other diseases, or certain medicines.

People in colder climates are more likely to develop Raynaud’s. It is also more common in women, people with a family history, and those over age 30.

Treatment for Raynaud’s may include drugs to keep the blood vessels open. There are also simple things you can do yourself, such as

  • Soaking hands in warm water at the first sign of an attack
  • Keeping your hands and feet warm in cold weather
  • Avoiding triggers, such as certain medicines and stress

NIH: National Heart, Lung, and Blood Institute

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